Build-a-Cell

Build-A-Cell

Open collaboration supporting the science and engineering of building synthetic cells.

 
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What is Build-A-Cell?

Cells are the fundamental "building blocks" that make up living organisms. Yet, we don't know exactly how cells were formed in the first place. We also don't know what all the molecules that make up any natural cell do. Finally, we can't yet put molecules together ourselves to make new synthetic cells.

Addressing the questions and challenges posed above requires significant collaboration and cooperation. The Build-a-Cell community welcomes all who wish to learn about and cooperate in the work of fully understanding and engineering a diversity of synthetic cells.

The future of biotechnology is in realizing fully understood, lineage agnostic organisms, beginning with single cells.

Building cells is hard. But, if we could better work together, then we should be able to build many cells for many purposes. Build-A-Cell is an open community supporting people working together to build a diversity of synthetic cells.

Why did we start Build-A-Cell?

Want to know more? Here’s a current, but brief overview of the synthetic cell field.

Roadmap:

Comprehensive roadmap, summarizing recent progress, and defining the most urgent needs of our field: Building Synthetic Cells─From the Technology Infrastructure to Cellular Entities, ACS SynBio, March 26, 2024, https://doi.org/10.1021/acssynbio.3c00724

 
 
 

Build-A-Cell is an NSF funded Research Coordination Network, award number 1901145.

 
 
 
 

Build-A-Cell holds regular working meetings to drive the field forward.

WORKSHOPS

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What are the Build a Cell Workshops?

Since 2017, Build a Cell has organized collaborative working meetings across the United States. Operating on the principle of “rough consensus and running codons”, the meetings are a space to share the forefront of cell-building research, brainstorm new ideas, establish and continue collaborations, and get collaborative work done in person. Build a Cell workshops have an open invitation policy—if you’re interested in the science, engineering, industry, ethics, or any other aspects of cell-building, we would love to see you there. Travel funding is available.

When are the Build A Cell Workshops?

Build a Cell workshops run approximately every six months, and are hosted by a rotating group of collaborators.

Full schedule and information about all workshops is here.

 

Build-a-Cell organizes two types of workshops: bi-annual large, all hands meetings, and thematic mini-workshops exploring single specific topic.

All workshops are open to all members and friends of Build-a-Cell community.

All workshops are free, there is no registration fee.

 

Mini-workshops on specific topics

Biosecurity Workshop I - considering safety and security of engineering synthetic cells. Link to workshop page.

Chemical Reaction Network modeling tutorials - link to info, recording and syllabus.

 

Find resources and information for building cells.

Synthetic cells 101

 

Collaboration

We believe in open source science and engineering, and collaborative development. Visit our engineering project for technical information, data, and analysis. Get in touch by joining the Slack.

If you’re interested in synthetic life research and would like to work with us, check out the job postings.

Working Groups

Most of Build-a-Cell activities happens in working groups. If you are interested in joining any of the working groups, contact the group lead.

If you’re curious why we’re doing what we’re doing, you can read about why we started Build-A-Cell.

 

We meet every week for online seminars.

Build-a-Cell seminar series

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Build-a-cell seminar series

The virtual journal club / research seminar series features weekly talks on all things synthetic cell engineering.

Everyone can join, and anybody is invited to volunteer to give a seminar or discuss a paper.

If you want to be notified about schedule and changes to the seminars, sign up here

Full seminar schedule is available here. If you would like to present a paper or your own research, please sign up here: seminar application form

 

Connecting researchers at all stages of career.

Build-a-Cell mentorship program

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Build-a-cell mentorship program

The Build-a-Cell community mentorship program connects people at different stages of career to share advice and experience.

Anybody can be a mentor! Most people have experience to share with those junior to them. If you are grad student, you could mentor an undergrad, etc.

Join here.

 

Moving the field forward

Build-a-Cell working groups

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Build-a-cell working groups

Most of Build-A-Cell activities are coordinated by working groups.

If you would like to join a working group or talk to group leaders, let us know through this form.

You can join any active working group. Some groups are actively soliciting new members, but you can get in touch with any group to see if they need a hand.

 

Build-A-Cell is an open collaboration working across the country and institutional divides.

TEAM

 
 

Who we are

 
 

Ready to help?

Get involved

 
 
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